Infusion Nursing Notes by Nufactor provides education, resources and support to promote successful patient therapy within the infusion nursing community.

HYQVIA® 10% — Learn About Expanded FDA-Approval for Treating PIDD and CIDP

HYQVIA® [Immune Globulin Infusion 10% (Human) with Recombinant Human Hyaluronidase] Solution, for subcutaneous administration was first FDA-approved in 2014 for primary immunodeficiency (PIDD) in adults. In 2023, HYQVIA® received expanded FDA-approval in PIDD to include pediatric patients aged 2-16. In 2024 HYQVIA® received FDA-approval for maintenance therapy in adults with chronic inflammatory demyelinating polyneuropathy (CIDP). [More]

SCIG and Blood Return

With Hizentra® 10 gm/50 mL prefilled syringes now commercially available, we have learned of some patients accidentally pulling out the syringe plunger when checking for blood return before administration. This may be related to the design and need for better dexterity and has resulted in wasted medication and delayed doses. [More]

How to Pool Medications into a Pooling Bag

By Candy Finley, RN, IgCN and Joe DiStefano, RPh

Pooling is the process of transferring the total dose of drug plus overfill into an empty IV bag ("pooling bag"). Although NuFACTOR prefers administering IVIG by spiking vials one at a time sequentially or adding drug directly into a bag of diluent (e.g., infliximab/Remicade®), there are some times when pooling is appropriate. These include lyophilized powder IVIG requiring reconstitution (e.g., Gammagard® SD and Carimmune®), HyQvia® (IG component only) and infliximab doses greater than 1000 mg. The process of pooling medications into a specially designed pooling bag is a relatively simple process. [More]

HYQVIA: Part 2

By Cindi Berry, RN BSN.

HYQVIA: Part 2 will discuss the administration steps and important aspects of HYQVIA therapy.

The administration and teaching of HYQVIA should be done by a well-trained RN. It is recommended that the treating RN has an extensive infusion background, and has been proficiently trained in IVIG and SCIG administration. [More]