Infusion Nursing Notes Blog | All posts tagged 'remicade'

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Administration, Common Side Effects and Dosing of INFLIXIMAB (REMICADE®)

5. July 2017 Candy Finley Infusion Basics (1)

By Candy Finley, RN, IgCN.

Infliximab is an intravenously administered genetically engineered monoclonal antibody that neutralizes inflammation caused by a protein called tumor necrosis factor alpha (TNFα) by binding to the soluble and transmembrane forms of TNFα with its receptors. Elevated concentrations of TNFα have been found in the tissues and fluids of patients with the Food and Drug Administration (FDA)-approved diagnoses. Infliximab controls the activity of several inflammatory chemicals. It is FDA-approved to treat rheumatoid arthritis, ankylosing spondylitis, Crohn's disease, plaque psoriasis, psoriatic arthritis and ulcerative colitis. Once established on treatment, symptoms should start to improve over a period of two to twelve weeks. [More]