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Nursing Notes
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Infusion Nursing Notes by Nufactor provides education, resources and support to promote successful patient therapy within the infusion nursing community.

Lyophilized Powder IVIG: Dilution, Reconstitution, and Pooling

15. February 2017 Derrek Blake Infusion Basics, IVIG Essentials (0)
By Derrek Blake, RN, IgCN, and Joe DiStefano, RPh.

Intravenous immune globulin (IVIG) is available as either a liquid or lyophilized (freeze-dried) powder. Initially only powder products were available, requiring reconstitution before administration. Over time, manufacturers changed their manufacturing process to achieve stability of the IgG molecules in a suspended or liquid state. By doing so, the task of reconstitution has been eliminated, making the powder products relatively obsolete. Depending on the brand, IVIG liquid is available in 5% and 10% concentrations. Depending on the brand, IVIG powder is reconstituted to yield a concentration between 3% and 12%. [More]

Pre-Medications Use, Side Effect Management & Intravenous Immune Globulin

23. March 2016 Joseph DiStefano IVIG Essentials (3)
By Joe DiStefano, RPh.

Intravenous immune globulin (IVIG) preparations are safe and effective treatments for a variety of medical conditions. Serious, but uncommon reactions occur, and include thromboembolic events, (e.g., pulmonary embolism, deep vein thrombosis, myocardial infarction, transient ischemic attack), renal dysfunction and acute renal failure. Mild to moderate side effects that occur during or after IVIG treatment are more common. These may include: headache, flushing, chills, myalgia, fatigue, low grade fever, changes in blood pressure and lower back pain. While many common side effects may be controlled by decreasing the IVIG infusion rate, administering physician-prescribed pre-medications can [More]

IVIG Side Effects

25. February 2014 Cindi Berry (5)
Do you know what the “expected” and “unexpected” side effects of intravenous immune globulin (IVIG) therapy are? More importantly, do you know how to manage them? [More]

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